WATERTOWN, Mass., March 28, 2022—As the COVID-19 pandemic transitions to endemic, a seventh annual in-depth report on physician sentiments shows that physician burnout and high levels of concerns about staffing shortages are a worldwide issue, with some at nearly double their 2021 levels. Nearly twice as many US physicians (45%) say they personally have experienced burnout in the past two years, compared to their European counterparts (25%). Sixty-two percent of American doctors, and 49% in Europe, are concerned about staffing shortages in their hospitals or clinics—while one in three US doctors, and one in four in Europe, have considered leaving the medical profession during the past year. For US physicians, in 2022 this number (34%) is nearly double what it was in 2021 (18%).